Explore our premium selection of enzymatically cleaved plant, marine, and bioactive peptide formulations designed for advanced skin barrier repair, hair strengtheners, and dietary supplements.
The global cosmetic and nutricosmetic industry is undergoing a paradigm shift toward molecularly targeted bioactive proteins. Hydrolyzed proteins represent the core foundation of modern dermatological formulation science.
In personal care and cosmetic chemistry, native macromolecules like intact collagen or keratin suffer from poor cutaneous penetration due to their high molecular weight (exceeding 300,000 Daltons). Through advanced enzymatic hydrolysis, long polypeptide chains are selectively cleaved into bioactive micro-peptides (ranging from 500 to 3,000 Daltons).
These low-molecular-weight peptides act as cellular signal transducers and moisture-binding hydro-complexes. When applied topically, they penetrate the stratum corneum, stimulate fibroblast synthesis, reduce transepidermal water loss (TEWL), and reinforce structural hair keratin.
China has established itself as the global epicenter for enzymatic hydrolysis research and bulk supply of cosmetic-grade peptides. By leveraging state-of-the-art bioreactors, membrane separation, and microbial fermentation technology, premier Chinese manufacturers deliver unparalleled batch consistency, scalable production, and competitive cost-efficiencies.
As global beauty brands transition from synthetic chemicals to sustainable, bio-based functional actives, Chinese bioactive protein suppliers lead the way in green biotechnology and custom peptide engineering.
Understanding the precise relationship between molecular weight distribution, amino acid profiles, and functional performance in cosmetic formulations.
| Protein Source | Typical Mol. Weight (Da) | Primary Active Peptides / Amino Acids | Core Cosmetic Application | Mechanism of Action |
|---|---|---|---|---|
| Hydrolyzed Yeast Protein | 500 – 1,500 Da | Nucleotides, Glutamic Acid, Lysine | Skin Barrier Repair & Microbiome Balancing | Upregulates Filaggrin expression, restores lipid barrier, accelerates stratum corneum recovery. |
| Hydrolyzed Collagen (Bovine/Marine) | 1,000 – 3,000 Da | Gly-Pro-Hyp Tripeptides, Hydroxyproline | Anti-Aging, Skin Elasticity & Dermal Firming | Triggers Type I & III collagen synthesis via TGF-beta signaling pathway in dermal fibroblasts. |
| Hydrolyzed Wheat Protein | 1,200 – 2,500 Da | Glutamine, Proline, Cystine | Hair Repair, Anti-Breakage & Conditioning | Forms a protective protective film on hair cuticle, increases tensile strength and cross-linking. |
| Hydrolyzed Soy & Pea Protein | 800 – 2,000 Da | Aspartic Acid, Arginine, Isoflavones | Vegan Skin Hydration & Cell Regeneration | Enhances natural moisturizing factor (NMF) production, scavenges reactive oxygen species (ROS). |
| Hydrolyzed Milk & Whey Protein | 1,000 – 3,500 Da | Lactoferrin, Branched-Chain Amino Acids (BCAAs) | Skin Smoothing, Elasticity & Sports Nutrition | Provides deep cellular nourishment, repairs damaged skin barrier, delivers highly absorbable BCAAs. |
Formulator's Insight: Selecting the correct Dalton weight is crucial. Low molecular weight hydrolysates (<1000 Da) penetrate deep into the dermis for biological signaling, whereas mid-range hydrolysates (1000–3000 Da) provide ideal film-forming, humectant, and conditioning properties on the skin surface and hair shaft.
A World-Class Bioactive Peptide Manufacturer Committed to Scientific Excellence and Global Quality Compliance.
Hangzhou Fderla Biology Co., Ltd. is a professional hydrolyzed protein manufacturer and bioactive peptide supplier based in Hangzhou, China. The company focuses on the research, development, production, and global export of high-quality protein hydrolysates for food, cosmetic, and nutritional applications.
With advanced biotechnology processes and strict quality control systems, Fderla Biology produces a wide range of hydrolyzed protein ingredients, including plant-based, animal-based, and marine-derived protein peptides. These materials are widely used in functional foods, dietary supplements, skincare formulations, hair care products, and sports nutrition solutions.
The company integrates modern enzymatic hydrolysis technology with scientific formulation expertise to ensure high bioavailability, easy absorption, and stable performance of its protein products. Each batch is carefully tested to meet international standards for purity, safety, and effectiveness.
Hangzhou Fderla Biology Co., Ltd. supports OEM and customized solutions for global clients, including ingredient formulation optimization, technical support, and bulk supply services. With a strong focus on innovation and sustainable biotechnology, the company continuously develops new functional peptide solutions for emerging market needs.
By combining scientific research, production excellence, and global service capability, Fderla Biology has become a trusted partner in the hydrolyzed protein and bioactive peptide industry, delivering reliable and high-performance ingredient solutions worldwide.
State-of-the-art enzymatic reactors, sterile ultrafiltration systems, microfiltration towers, and ISO-certified analytical testing laboratories ensuring unmatched ingredient purity.
Customized functional peptide solutions engineered for cosmetic chemists, product developers, and brand owners worldwide.
Recommended Active: Hydrolyzed Bovine / Marine Collagen Peptides (< 1,000 Da).
Formulated into high-performance facial serums and anti-wrinkle night creams. Small-chain tripeptides stimulate integrin receptors on fibroblast cell membranes, triggering intracellular signals for native collagen (Type I) and elastin gene transcription.
Suggested Dosage: 1.5% – 5.0% pH Range: 5.0 – 6.5
Recommended Active: Hydrolyzed Yeast Protein Liquid / Powder.
Rich in essential amino acids, beta-glucans, and low molecular peptides. It replenishes intercellular lipids, repairs compromised stratum corneum post-chemical peel, and feeds beneficial cutaneous microflora.
Suggested Dosage: 2.0% – 8.0% pH Range: 4.5 – 6.0
Recommended Active: Hydrolyzed Wheat & Soy Proteins.
Ideal for damaged, bleached, or heat-styled hair products. High cysteine content allows cross-linking with damaged keratin disulfide bonds, filling cuticle voids and increasing hair tensile strength by up to 35%.
Suggested Dosage: 1.0% – 4.0% pH Range: 4.0 – 6.5
Ensuring seamless international trade, complete raw material traceability, and regulatory compliance across North America, the European Union, Asia-Pacific, and the Middle East.
All cosmetic-grade hydrolyzed proteins produced by Hangzhou Fderla Biology Co., Ltd. strictly adhere to EU Cosmetic Regulation (EC) No 1223/2009. Comprehensive safety dossiers, including Certificate of Analysis (CoA), Safety Data Sheets (SDS), Technical Data Sheets (TDS), allergen reports, and non-GMO statements are fully available for regulatory filing.
Our manufacturing facilities comply with US FDA Voluntary Cosmetic Registration Program (VCRP) requirements and modern MoCRA regulations, ensuring zero heavy metal contamination (Pb < 5ppm, As < 1ppm, Cd < 1ppm, Hg < 0.1ppm) and negative microbiological pathogens.
To accommodate diverse market demographics and regional cultural preferences, our collagen, plant, and yeast hydrolysates carry internationally recognized Halal (JAKIM/MUI compliant) and Kosher certifications.
We offer 100% cruelty-free, vegan-suitable plant-based protein hydrolysates (Soy, Pea, Rice, Wheat) tailored for Clean Beauty brands seeking sustainable, ethically sourced, and microplastic-free cosmetic raw materials.
Pioneering next-generation cosmetic peptide synthesis through artificial intelligence, precision fermentation, and green extraction techniques.
Utilizing bioinformatic algorithms to model enzyme-substrate cleavage patterns, enabling targeted extraction of hyper-specific signaling peptide sequences with max receptor affinity.
Scaling up non-animal recombinant humanized collagen and keratin hydrolysates using synthetic biology and yeast expression vectors for 100% bio-identical efficacy.
Implementing eco-friendly enzymatic cascade extraction processes that upcycle botanical side-streams into high-value functional cosmetic hydrolysates with zero carbon footprint.
Explore the rest of our premium high-purity protein products for cosmetics, food additives, and pet nutrition applications.
Technical, commercial, and regulatory guidance for procurement managers and product formulators.
Native proteins have high molecular weights (typically >100 kDa) that prevent penetration through the skin barrier. Hydrolyzed proteins undergo controlled enzymatic digestion, reducing their size to under 3,000 Daltons (or <1,000 Da for bio-peptides). This enables deep stratum corneum absorption, active cellular signaling, improved water-binding capacity, and complete cold-water solubility without gelling or precipitation.
Hangzhou Fderla Biology Co., Ltd. utilizes dual endo- and exo-peptidase multi-stage enzymatic technology combined with precise temperature and pH feedback control loops. This ensures selective cleavage at specific amino acid sites, preventing bitter peptide generation in food grade lines and maximizing bioactive peptide yield, color stability, and odor neutrality for high-end cosmetic emulsions.
Yes! Our low-molecular-weight hydrolysates (such as Hydrolyzed Yeast Protein Liquid and Marine Collagen Peptides) are fully water-soluble and yield clear, transparent solutions across a broad pH spectrum (pH 4.0 to 8.0). They exhibit superior thermal stability and ethanol compatibility (up to 20% ethanol volume), making them ideal for essences, clear serums, and facial toners.
Every commercial lot produced by Fderla Biology comes with a comprehensive documentation package, including Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS/SDS), Technical Data Sheet (TDS), Heavy Metal & Pesticide Residue Test Reports, Microbiological Compliance Certificates, Non-GMO Statements, and BSE/TSE-Free Certificates for collagen items.
Absolutely. We offer comprehensive OEM/ODM customization services. We can tailor the target molecular weight distribution (e.g., custom cutoffs at 500 Da, 1000 Da, or 2000 Da via nanofiltration), customize active concentration percentages, and adjust liquid/powder forms. We also support bulk supply, custom packaging (from 1kg aluminum foil bags to 25kg fiber drums), and custom formulation blending for brand owners.
Fderla Biology
