High-purity bio-functional protein hydrolysates optimized for pharmaceutical cosmetics, keratin hair therapy systems, and high-absorption nutricosmetics across Coimbra's biotech corridor.
Hangzhou Fderla Biology Co., Ltd. is a leading professional hydrolyzed protein manufacturer and bioactive peptide supplier based in Hangzhou, China. The company focuses on the advanced research, continuous development, precision production, and global export of high-quality protein hydrolysates for food, cosmetic, pharmaceutical, and nutritional applications.
With state-of-the-art biotechnology processes and strict quality control systems, Fderla Biology produces a comprehensive portfolio of hydrolyzed protein ingredients, including plant-based, animal-based, and marine-derived protein peptides. These specialized materials are widely integrated into functional foods, dietary nutricosmetic supplements, clinical skincare formulations, professional hair restoration products, and athletic sports nutrition solutions worldwide.
By integrating modern enzymatic hydrolysis technology with scientific formulation expertise, Fderla Biology ensures high bioavailability, optimal cuticular substantivity, rapid dermal absorption, and exceptional batch-to-batch stability. Each production batch undergoes rigorous testing to meet strict international standards for chemical purity, biological safety, and clinical effectiveness.
Connect with Our Technical TeamAnalyzing the unique scientific, cosmetic, and industrial requirements of the Coimbra regional cluster—from academic R&D spin-offs to commercial cosmeceutical manufacturers.
Coimbra, home to the prestigious University of Coimbra and Instituto Pedro Nunes (IPN), represents Portugal's epicenter for biomedical and dermatological innovation. Local research facilities require ultra-pure, standardized Hydrolyzed Keratin peptides (CAS 69430-36-0) with guaranteed molecular weights for biomaterial research, tissue engineering matrices, and micro-encapsulated skin delivery vehicles.
The growing concentration of contract cosmetic manufacturers and indie beauty labs in the Centro Region demands high-performance bioactive ingredients. Local brands prioritize water-soluble hydrolyzed keratin powder (Purity ≥98%) that seamlessly blends into anti-pollution serums, cuticle conditioning ampoules, and post-treatment restorative hair creams without cloudiness or odor instability.
European Union sustainability directives and Coimbra’s eco-conscious consumer base mandate ethically sourced, zero-waste protein derivatives. Hangzhou Fderla Biology leverages sustainable enzymatic upcycling of natural keratin sources, providing Coimbra partners with eco-certified peptides that align with EU Green Deal goals and clean-label cosmetic standardizations.
Unlike standard un-hydrolyzed keratin proteins which possess excessively large molecular weights (>30,000 Da) that remain purely film-forming on the exterior surface of the hair shaft, Hangzhou Fderla’s controlled enzymatic hydrolysis breaks disulfide bonds into micro-peptides ranging from 500 to 2,000 Da. This precise molecular targeting allows deep penetration into the inner cortex layer, restoring inter-microfibrillar protein structures damaged by thermal styling, bleaching, or environmental oxidative stress typical of Mediterranean climates.
Engineered through enzymatic cleavage to maximize cystine retention, amino acid integrity, and multi-functional performance across cosmetic and nutracosmetic systems.
| Test Parameter | Cosmetic Grade Standard | Food / Nutracosmetic Grade Standard | Test Method / Protocol |
|---|---|---|---|
| Appearance | Light yellow to off-white powder / clear liquid | Off-white fine soluble powder | Visual inspection |
| Protein Content (Dry Basis) | ≥ 90.0% | ≥ 95.0% - 98.0% | Kjeldahl Method (N x 6.25) |
| Molecular Weight (Mw) | 800 - 2,000 Da | 500 - 1,500 Da | HPLC Gel Filtration |
| pH Value (10% Solution) | 5.0 - 7.5 | 5.5 - 7.0 | Potentiometric measurement |
| Loss on Drying | ≤ 6.0% | ≤ 5.0% | Gravimetric (105°C, 4h) |
| Heavy Metals (as Pb) | ≤ 10 ppm | ≤ 5 ppm | ICP-MS Spectrometry |
| Arsenic (As) | ≤ 1.0 ppm | ≤ 0.5 ppm | Atomic Fluorescence |
| Total Plate Count | ≤ 100 CFU/g | ≤ 1000 CFU/g | ISO 4833-1 Standard |
How our Hydrolyzed Keratin Protein delivers targeted performance across hair care, skincare, nails, and nutricosmetics.
In professional hair care formulations, broken disulfide bonds cause frizz, porosity, and structural weakness. Hydrolyzed Keratin peptides bind selectively to damaged keratin fibrils via hydrogen and ionic bonding.
Hydrolyzed keratin provides natural moisture-binding properties (NMF mimicry) due to its high concentration of hydrophilic amino acids such as serine, glutamic acid, and aspartic acid.
Food Grade Hydrolyzed Keratin Peptide Powder (CAS 69430-36-0) offers a bioavailable oral source of bio-active sulfur and essential building block amino acids required for endogenous keratin synthesis in hair follicles and nail beds.
Low molecular weight oligopeptides (< 1,000 Da) are rapidly absorbed via PepT1 transporters in the human digestive system.
De-flavored and de-odorized using advanced carbon filtration technology, suitable for beauty drink mixes and capsules.
Combines seamlessly with Marine Collagen Peptides, Hyaluronic Acid, Zinc, and Biotin for comprehensive nutracosmetic kits.
Explore our full spectrum of raw protein powders, concentrated liquid hydrolysates, OEM salon treatment kits, and specialty multi-protein complexes.
Navigating EU cosmetic regulations with full transparency, documentation, and safety certifications for hassle-free importation into Coimbra and the wider European Union.
Fully compliant ingredient dossier support, INCI breakdown, IFRA status certificates, and toxicological profiles ready for CPNP portal notification across Portugal and EU member states.
Our Hydrolyzed Keratin (CAS: 69430-36-0 / EINECS: 274-001-1) complies with REACH substance evaluation criteria, ensuring seamless clearance at Portuguese customs and zero supply chain disruption.
Manufactured under strict Good Manufacturing Practices (GMP). Every batch is delivered with a comprehensive Certificate of Analysis (COA) detailing heavy metal, microbiological, and purity metrics.
Pioneering sustainable enzymatic extraction and bio-engineered peptide sequence matching for advanced cosmeceutical applications.
Moving beyond standard protein hydrolysates, Hangzhou Fderla Biology is developing targeted peptide sequences tailored specifically to mimic the exact tri-peptide and tetra-peptide repeat units of natural human hair cortex keratin (KAP proteins). This innovation enables 3x faster cellular adhesion and superior keratinocyte repair rates for damaged hair and nail beds.
Designed for premium dermatological formulations in Europe, our upcoming liposome-encapsulated liquid keratin hydrolysate allows sustained trans-epidermal penetration into deeper epidermal layers, providing continuous structural hydration and micro-barrier repair for compromised skin conditions.
Expert answers regarding bulk ordering, formulation dynamics, technical specifications, and shipping to Central Portugal.
Hydrolyzed Keratin Powder (98% purity) offers maximum shelf stability (24-36 months), zero preservation requirements, and lower shipping costs for long-distance export. Liquid bulk formats (typically 20%-50% active protein concentration) are pre-solubilized for immediate incorporation into cold-process shampoo, conditioner, and ampoule manufacturing lines without requiring dissolving tanks.
Every lot undergoes High-Performance Liquid Chromatography (HPLC) molecular weight profiling, Kjeldahl nitrogen titration, heavy metal testing (ICP-MS), and microbial analysis. Certificates of Analysis (COA) are issued for each shipment to ensure exact alignment with EU Regulation (EC) No 1223/2009 standards.
Yes. Our Food Grade Hydrolyzed Keratin Peptide Powder (90%+ protein content, CAS 69430-36-0) is processed using enzyme-only hydrolysis without hazardous chemical residues. It meets strict food additive safety limits, heavy metal thresholds (<5 ppm), and microbial purity rules suitable for dietary capsules and instant collagen-keratin drink premixes.
For daily maintenance shampoos and conditioners, we recommend 0.5% - 2.0% active concentration. For intensive repair masks, serums, and ampoules, 2.0% - 5.0% is optimal. In professional 12% Brazilian keratin smoothing treatments, custom concentrations ranging up to 10%-15% total protein complexes are utilized depending on target straightening strength.
Air freight samples and urgent small batches arrive in Portugal within 5 to 7 business days via DHL/FedEx. Standard bulk ocean freight shipments to Lisbon or Leixões (Porto) ports—followed by direct transport to Coimbra—typically take 25 to 35 days. We also offer DDP (Delivered Duty Paid) shipping solutions handling all customs formalities.
Yes. Hangzhou Fderla Biology utilizes upcycled, natural keratin byproduct sources (such as sheep wool or poultry feathers) processed via bio-enzymatic cleavage. This circular economy approach avoids synthetic chemical waste, reduces environmental footprint, and complies with EU sustainability standards.
Proteins above 30,000 Da cannot enter the hair shaft or stratum corneum and only form a temporary film. Hydrolyzed keratin peptides optimized between 500 Da and 2,000 Da easily pass through cuticle gaps into the cortex, bonding with damaged polypeptide chains to deliver permanent structural reinforcement.
Yes. We provide complete OEM/ODM services including formulation customization, bottle and packaging design, fragrance profiling (e.g., Brazilian Argan oil, coconut, botanical notes), and bulk finished kit packaging (shampoo, straightening cream, repair mask) ready for retail in Coimbra salons.
Fderla Biology
